drugset / Trial / NCT00000929

A Study of the Effects of Advantage 24 on the Rectum

NCT00000929

Prevention

Summary

The purpose of this study is to see if it is safe and acceptable for homosexual male couples, where both partners have the same HIV status, to use Advantage 24 during anal intercourse. Advantage 24 is a spermicide (a chemical that kills sperm). Much research and development is being done with chemicals that can be controlled by the receptive partner to prevent the spread of HIV and other sexually transmitted diseases (STDs). Advantage 24 currently is used in the vagina as a form of birth control. The safety of Advantage 24 is particularly important for HIV-positive men because they have a greater chance of serious reaction to Advantage 24 due to other HIV-related conditions.

Timeline

Start
Primary completion
Completion
1999-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Nonoxynol-9 Small molecule Rectal