drugset / Trial / NCT00000946

A Study to Test the Safety of Three Experimental HIV Vaccines

NCT00000946 ↗

Double-blindPrevention

Summary

The purpose of this study is to test three experimental HIV vaccines. This study will look at whether it is safe to give these vaccines together and how the immune system responds to the vaccines. There are a number of studies being performed to test HIV vaccines. The vaccines that seem to be the most promising are canarypox vaccines, known as ALVAC vaccines. The three experimental HIV vaccines used in this study are called ALVAC-HIV vCP205, HIV-1 SF-2 p24, and HIV-1 SF-2 rgp120. The HIV-1 SF-2 p24 and HIV-1 SF-2 rgp120 vaccines are mixed with an adjuvant, which is a substance that increases immune response.

Timeline

Start
—
Primary completion
—
Completion
2001-03

Drugs

EvaluationDrugModalityDoseRoute
Subject ALVAC-HIV MN120TMG (vCP205) Vaccine — —
Subject ALVAC-RG Rabies Glycoprotein (vCP65) Unknown — —
Subject HIV-1 SF-2 p24 Vaccine — —
Subject rgp120/HIV-1 SF-2 Vaccine — —