drugset / Trial / NCT00002214

Phase I Trial of S-1153 in Patients With HIV Infection

NCT00002214

Phase 1 Completed 40 enrolled Lexigen Pharmaceuticals
Treatment

Summary

To assess the toxicity profile and determine the maximum tolerated dose (MTD), if possible, of S-1153 administered orally 3 times daily for 14 days. To investigate the clinical pharmacokinetic parameters for S-1153. To assess anti-HIV activity associated with S-1153 administration through evaluation of CD4 and viral load measurements.

Timeline

Start
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Capravirine Small molecule Oral