drugset / Trial / NCT00002333

A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine

NCT00002333

Phase 2 Completed 900 enrolled Hoffmann-La Roche
Double-blindTreatment

Summary

To compare the safety, tolerance, and efficacy of saquinavir mesylate (Ro 31-8959) alone, zalcitabine (dideoxycytidine; ddC) alone, and both in combination, in patients discontinuing or unable to take zidovudine (AZT).

Timeline

Start
Primary completion
Completion

Publications

  • Background Revicki D, Swartz C. Quality of life outcomes of saquinavir, zalcitabine and combination saquinavir-zalcitabine therapy for advanced HIV-infection. Conf Retroviruses Opportunistic Infect. 1997 Jan 22-26;4th:113 (abstract no 266)

Drugs

EvaluationDrugModalityDoseRoute
Subject Saquinavir Small molecule
Subject Zalcitabine Small molecule