drugset / Trial / NCT00002619

Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Glioblastoma Multiforme or Brain Stem Tumors

NCT00002619

Phase 2 Completed 60 enrolled NYU Langone Health
Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow or peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill tumor cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy followed by autologous bone marrow or peripheral stem cell transplantation in treating patients with glioblastoma multiforme or brain stem tumors.

Timeline

Start
1994-09
Primary completion
2000-04
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Thiotepa Other / unclassified
Background filgrastim Protein / enzyme biologic