drugset / Trial / NCT00002747

Surgery and Radiation Therapy With or Without Chemotherapy in Treating Patients With Mouth Cancer

NCT00002747 ↗

Phase 3 Unknown 240 enrolled European Institute of Oncology
RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known if surgery plus radiation therapy is more effective with or without chemotherapy for treating mouth cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery and radiation therapy with or without chemotherapy in treating patients with stage II, stage III, or stage IV mouth cancer.

Timeline

Start
1992-09
Primary completion
—
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified — Intravenous
Subject fluorouracil Small molecule — Intravenous

Indications