drugset / Trial / NCT00003046

Interleukin-12 in Treating Patients With Cancer in the Abdomen

NCT00003046

Non-randomizedSingle-groupOpen-labelTreatment

Summary

RATIONALE: Interleukin-12 may kill tumor cells by stimulating a person's white blood cells to kill cancer cells. PURPOSE: Phase I trial to study the effectiveness of interleukin-12 in treating patients with cancer in the abdomen.

Timeline

Start
1997-08
Primary completion
2001-10
Completion
2001-10

Publications

  • Results Lenzi R, Kudelka AP, Veschraegen C, et al.: Intraperitoneal (IP) bioimmunologic responses in patients with ovarian and gastrointestinal cancers at a low toxicity dosing schedule of IP recombinant interleukin-12 (rhIL-12). [Abstract] Proc Am Assoc Cancer Res 40: A3778, 573, 1999.

Drugs

EvaluationDrugModalityDoseRoute
Subject interleukin-12 Protein / enzyme biologic Other