drugset / Trial / NCT00003236
Chemotherapy in Treating Women With Previously Treated Metastatic Breast Cancer
RandomizedTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase II trial to compare the effectiveness of ISIS 5132 with ISIS 3521 in treating women who have metastatic breast cancer that has not responded to previous therapy.
Timeline
- Start
- 1998-07-13
- Primary completion
- 2002-06
- Completion
- —
Publications
- Results Gradishar WJ, O'Neill A, Cobleigh M, et al.: A phase II trial with antisense oligonucleotide ISIS 3521/Cgp 64128a in patients (Pts) with metastatic breast cancer (MBC): ECOG trial 3197. [Abstract] Proceedings of the American Society of Clinical Oncology 20: A-171, 2001.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ISIS 3521 | Antisense oligonucleotide | — | Intravenous |
| Subject | ISIS 5132 | Antisense oligonucleotide | — | Intravenous |