drugset / Trial / NCT00003239
Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with cytarabine and homoharringtonine and biological therapy with interferon alfa in treating patients with chronic phase chronic myelogenous leukemia.
Timeline
- Start
- 1998-03
- Primary completion
- 2001-10
- Completion
- 2001-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cytarabine | Small molecule | — | Subcutaneous |
| Subject | Homoharringtonine | Small molecule | — | — |
| Subject | interferon alfa-2b | Protein / enzyme biologic | — | Subcutaneous |