drugset / Trial / NCT00003707
Combination Chemotherapy in Treating Patients With Advanced Cancer
Phase 1
Completed
22 enrolled
The University of Texas Health Science Center at San Antonio
National Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of combining R115777 with gemcitabine in treating patients with advanced cancer.
Timeline
- Start
- 1998-10
- Primary completion
- 2002-11
- Completion
- 2002-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | tipifarnib | Small molecule | — | Oral |
| Background | Gemcitabine | Small molecule | — | Intravenous |