drugset / Trial / NCT00003883
Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation
Phase 3
Completed
578 enrolled
Fred Hutchinson Cancer Center
National Cancer Institute (NCI) · collab
RandomizedSupportive care
Summary
RATIONALE: Giving itraconazole or fluconazole may be effective in preventing infections in patients undergoing peripheral stem cell or bone marrow transplantation. It is not yet known whether itraconazole is more effective than fluconazole for preventing infections. PURPOSE: Randomized phase III trial to compare the effectiveness of itraconazole with fluconazole to prevent infections in patients undergoing peripheral stem cell or bone marrow transplantation.
Timeline
- Start
- 1998-10
- Primary completion
- 2002-07
- Completion
- 2002-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | — | Oral |
| Subject | Itraconazole | Small molecule | — | Oral |