drugset / Trial / NCT00003970
Genetic Testing Plus Irinotecan in Treating Patients With Solid Tumors or Lymphoma
NaSingle-groupOpen-labelTreatment
Summary
Phase I trial to study genetic testing and the effectiveness of irinotecan in treating patients who have solid tumors and lymphoma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Genetic testing for a specific enzyme may help doctors determine whether side effects from or response to chemotherapy are related to a person's genetic makeup
Timeline
- Start
- 1999-01
- Primary completion
- 2003-10
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Irinotecan | Small molecule | — | Intravenous |
Indications
AIDS-related primary central nervous system lymphoma
Burkitt lymphoma
Hodgkins lymphoma
MALT lymphoma
adult T-cell leukemia/lymphoma
anaplastic large cell lymphoma
angioimmunoblastic T-cell lymphoma
cancer of unknown primary site
central nervous system non-hodgkin lymphoma
chronic lymphocytic leukemia/small lymphocytic lymphoma
diffuse large B-cell lymphoma
immunodeficiency-associated lymphoproliferative disease
intraocular lymphoma
large-cell immunoblastic lymphoma
mantle cell lymphoma
mycosis fungoides and variants
nodal marginal zone B-cell lymphoma
small intestine lymphoma
splenic marginal zone lymphoma