drugset / Trial / NCT00004080

Gene Therapy in Treating Patients With Recurrent or Progressive Brain Tumors

NCT00004080

Treatment

Summary

RATIONALE: Inserting the gene for p53 into a person's brain cells may improve the body's ability to fight cancer. PURPOSE: Phase I trial to study the effectiveness of p53 gene therapy with SCH-58500 in treating patients who have recurrent, or progressive glioblastoma multiforme, anaplastic astrocytoma, or anaplastic mixed glioma that can be removed during surgery.

Timeline

Start
1999-12
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject SCH-58500 Gene therapy (AAV / viral vector) Other