drugset / Trial / NCT00004141
Combination Chemotherapy Plus Biological Therapy in Treating Patients With Metastatic Melanoma
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Biological therapies use different ways to stimulate the immune system and stop cancer cell from growing. Combining more than one drug with different types of biological therapies may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus biological therapy in treating patients who have metastatic melanoma.
Timeline
- Start
- 1998-08
- Primary completion
- 2003-01
- Completion
- 2006-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | Intravenous |
| Subject | Dacarbazine | Small molecule | 660 mg/m2 | Intravenous |
| Subject | sargramostim | Protein / enzyme biologic | 450 mg/m2 | Subcutaneous |