drugset / Trial / NCT00004275
Oxandrolone Compared With a Placebo on Growth Rate in Girls With Growth Hormone-Treated Turner's Syndrome
Phase 2
Completed
80 enrolled
National Institute of Neurological Disorders and Stroke (NINDS)
Jefferson Medical College of Thomas Jefferson University · collab
Treatment
Summary
RATIONALE: Turner's syndrome is a disease in which females are missing all or part of one X chromosome and do not produce the hormones estrogen and androgen. Giving growth hormone may help girls with Turner's syndrome attain a more normal height. It is not yet known if growth hormone is more effective with or without oxandrolone for Turner's syndrome. PURPOSE: Randomized phase II trial to study the effectiveness of oxandrolone in girls who have growth hormone-treated Turner's syndrome.
Timeline
- Start
- 1999-10
- Primary completion
- 2007-08
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oxandrolone | Small molecule | — | Oral |
| Background | Somatropin | Protein / enzyme biologic | — | Subcutaneous |