drugset / Trial / NCT00004440
Study of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis
Completed
75 enrolled
FDA Office of Orphan Products Development
Case Western Reserve University · collab
RandomizedOpen-labelTreatment
Summary
OBJECTIVES: I. Determine the effect of different doses of ibuprofen on neutrophil (polymorphonuclear leukocyte; PMN) delivery to a mucosal surface (the oral mucosa) in patients with cystic fibrosis and healthy controls. II. Determine the duration of effect (and possible rebound effect) of ibuprofen on PMN delivery to a mucosal surface in these patients.
Timeline
- Start
- 1996-08
- Primary completion
- —
- Completion
- 1999-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ibuprofen | Small molecule | — | Oral |