Phase III Randomized Study of Sodium Dichloroacetate in Children With Congenital Lactic Acidosis

Summary

OBJECTIVES: I. Compare the safety of sodium dichloroacetate (DCA) vs placebo in children with congenital lactic acidosis. II. Determine the quality of life of these patients. III. Determine the pharmacokinetics and metabolic fate of DCA over the course of drug administration in these patients.

Timeline

Start

1998-10

Primary completion

—

Completion

2002-09

Drugs

Indications