drugset / Trial / NCT00004492

Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia

NCT00004492

Phase 1/2 Completed 20 enrolled University of North Carolina
RandomizedTreatment

Summary

OBJECTIVES: I. Compare the efficacy of hydroxyurea with or without clotrimazole in terms of limiting the severity of anemia and the rate of hemolysis in patients with sickle cell anemia.

Timeline

Start
1999-10
Primary completion
Completion
2001-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Clotrimazole Unknown Oral
Subject Hydroxyurea Other / unclassified Oral

Indications