drugset / Trial / NCT00004734

Vitamin Therapy for Prevention of Stroke

NCT00004734

RandomizedDouble-blindPrevention

Summary

A stroke occurs when part of the brain is damaged from lack of normal blood supply. This may result in difficulty with feeling, speech, muscle strength or coordination, movement, thinking, or other brain functions. Having a stroke increases the risk of another stroke occurring in the future. Higher blood levels of a natural chemical known as homocysteine may contribute to hardening of the arteries in the brain or heart and increase the risk of stroke or heart attack. Folic acid, vitamin B6 (pyridoxine), and vitamin B12 (cyanocobalamin) may lower blood levels of homocysteine and reduce the risk of having another stroke or a heart attack.

Timeline

Start
1996-09
Primary completion
Completion
2004-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Pyridoxine Unknown
Subject Vitamin B12 Other / unclassified
Subject folic acid Other / unclassified