drugset / Trial / NCT00004796

Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis

NCT00004796

Treatment

Summary

OBJECTIVES: I. Assess the effect of lactulose on the circadian rhythm of plasma melatonin in patients with subclinical hepatic encephalopathy. II. Assess the intrasubject variability of circadian melatonin levels and neuropsychological tests. III. Assess which elements of the neuropsychological test battery show the response to lactulose.

Timeline

Start
1994-11
Primary completion
Completion
1997-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Lactulose Other / unclassified