Study of Clozapine for the Treatment of Psychosis in Patients With Idiopathic Parkinson's Disease

Summary

OBJECTIVES: I. Determine the efficacy and tolerability of clozapine in ameliorating psychosis in patients with idiopathic Parkinson's disease (PD). II. Determine the adverse effects of clozapine on motor function in this patient population. III. Determine the safety of clozapine in psychotic PD patients taking multiple anti-PD medications. IV. Describe the phenomenology of drug induced psychosis in PD.

Timeline

Start

1993-10

Primary completion

—

Completion

1997-11

Drugs

Indications