drugset / Trial / NCT00005060

Combination Chemotherapy and Surgery in Treating Patients With Locally Advanced Stomach Cancer

NCT00005060 ↗

Phase 3 Completed 240 enrolled Swiss Cancer Institute
RandomizedFactorialOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery may kill more tumor cells. It is not yet known if chemotherapy followed by surgery is more effective than surgery followed by chemotherapy for stomach cancer. PURPOSE: This randomized phase III trial is studying surgery followed by combination chemotherapy to see how well it works compared to combination chemotherapy followed by surgery in treating patients with locally advanced stomach cancer.

Timeline

Start
1999-11
Primary completion
2005-11
Completion
2006-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cisplatin Other / unclassified — Intravenous
Comparator Docetaxel Small molecule — Intravenous
Comparator fluorouracil Small molecule — Intravenous

Indications