drugset / Trial / NCT00005818

SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer

NCT00005818

Phase 1/2 Completed 68 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase I/II trial to study the effectiveness of combining SU5416 and irinotecan in treating patients who have advanced colorectal cancer. SU5416 may stop the growth of colorectal cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die

Timeline

Start
2000-03
Primary completion
2003-03
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject semaxanib Small molecule Intravenous
Background Irinotecan Small molecule Intravenous