Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Summary

OBJECTIVES: I. Evaluate the toxicity of amifostine in patients with bone marrow failure related to Fanconi's anemia. II. Determine the efficacy of this treatment regimen in this patient population. III. Evaluate the effect of this treatment regimen on bone marrow progenitor cell proliferation and peripheral blood mononuclear cell apoptosis in these patients.

Timeline

Start

2000-04

Primary completion

—

Completion

—

Drugs

Indications