drugset / Trial / NCT00006968

Pentostatin Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Kidney Cancer

NCT00006968

Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with donor peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of pentostatin followed by peripheral stem cell transplantation in treating patients who have advanced kidney cancer.

Timeline

Start
2000-09
Primary completion
2004-09
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentostatin Small molecule Intravenous
Background Cyclosporine Peptide Intravenous
Background filgrastim Protein / enzyme biologic Intravenous

Indications