drugset / Trial / NCT00007826

Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer

NCT00007826

Phase 1/2 Unknown Onyvax
Open-labelTreatment

Summary

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Vaccines made from cancer cells may make the body build an immune response to kill colorectal tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of monoclonal antibody therapy and/or vaccine therapy in treating patients who have locally advanced or metastatic colorectal cancer.

Timeline

Start
2000-04
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject 105AD7 Monoclonal antibody Other
Background BCG vaccine Vaccine Other
Background alum adjuvant Unknown Intramuscular

Indications