drugset / Trial / NCT00010322
Toremifene With or Without Atamestane in Treating Postmenopausal Women With Metastatic Breast Cancer
Treatment
Summary
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Toremifene may fight breast cancer by blocking the uptake of estrogen by the tumor cells. Atamestane may fight breast cancer by blocking the production of estrogen. It is not yet known if toremifene is more effective with or without atamestane. PURPOSE: Randomized phase III trial to compare the effectiveness of toremifene with or without atamestane in treating postmenopausal women who have metastatic breast cancer.
Timeline
- Start
- 2000-10
- Primary completion
- 2001-05
- Completion
- 2001-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atamestane | Small molecule | — | Oral |
| Subject | Toremifene | Small molecule | — | Oral |