7-hydroxystaurosporine and Cisplatin in Treating Patients With Advanced Malignant Solid Tumors

Summary

Phase I trial to study the effectiveness of combining UCN-01 with cisplatin in treating patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. UCN-01 may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth and may help cisplatin kill more cancer cells by making tumor cells more sensitive to the drug.

Timeline

Start

2001-03

Primary completion

2007-01

Completion

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Drugs

Indications