drugset / Trial / NCT00015067

Cocaine-Methylphendidate Interaction Study - 4

NCT00015067

CrossoverTreatment

Summary

The purpose of this study is to attempt to identify possible dangerous interactions between cocaine and methylphenidate (MPD). Additional objectives are to determine: a) if MPD reduces the craving and high for cocaine; b) if there are pharmacokinetic and pharmacodynamic interactions between cocaine and MPD; and c) the relationship between cocaine and benzoylecgonine (BE) levels in plasma and BE levels in urine.

Timeline

Start
1997-12
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylphenidate Small molecule 60 mg
Subject Methylphenidate Small molecule 90 mg