drugset / Trial / NCT00015977

Vaccine Therapy Plus Interleukin-12 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00015977

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Vaccines made from a patient's white blood cells may make the body build an immune response to kill cancer cells. Interleukin-12 may kill cancer cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill cancer cells. Combining vaccine therapy with interleukin-12 may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of vaccine therapy combined with interleukin-12 in treating patients who have metastatic prostate cancer that has not responded to hormone therapy.

Timeline

Start
2001-11
Primary completion
2003-03
Completion
2005-01

Drugs

EvaluationDrugModalityDoseRoute
Subject PSA prostate cancer vaccine Vaccine Subcutaneous
Subject interleukin-12 Protein / enzyme biologic Subcutaneous

Indications