drugset / Trial / NCT00024336

Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma

NCT00024336

Treatment

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Tamoxifen may kill tumor cells by blocking the enzymes necessary for cell growth. Combining radiation therapy with tamoxifen may be effective in treating newly diagnosed brain stem glioma. PURPOSE: Phase II trial to study the effectiveness of combining radiation therapy and tamoxifen in treating children who have newly diagnosed brain stem glioma.

Timeline

Start
1999-08
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Tamoxifen Small molecule Oral