drugset / Trial / NCT00026351

Pentostatin and Rituximab in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

NCT00026351

Phase 2 Completed Pharmatech Oncology
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining chemotherapy with monoclonal antibody therapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining pentostatin and rituximab in treating patients who have non-Hodgkin's lymphoma or chronic lymphocytic leukemia.

Timeline

Start
2000-12
Primary completion
Completion
2003-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentostatin Small molecule Intravenous
Subject Rituximab Monoclonal antibody Intravenous

Indications