drugset / Trial / NCT00030186

Open Study of CEP-701 in Patients With Refractory Acute Myeloid Leukemia With FLT-3 Mutation

NCT00030186

Phase 2 Completed 37 enrolled Cephalon
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the response rate of patients with refractory, relapsed or poor risk AML expressing FLT-3 activating mutations, when administered CEP-701 at a dosage of 60 mg 2 times a day.

Timeline

Start
2002-01
Primary completion
2003-02
Completion
2003-02

Drugs

EvaluationDrugModalityDoseRoute
Subject lestaurtinib Small molecule 40 mg Oral
Subject lestaurtinib Small molecule 60 mg Oral
Subject lestaurtinib Small molecule 80 mg Oral