drugset / Trial / NCT00030823

Vaccine Therapy in Treating Patients at High Risk for Breast Cancer Recurrence

NCT00030823

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Vaccines may make the body build an immune response and decrease the recurrence of breast cancer. PURPOSE: Pilot trial to study the effectiveness of vaccine therapy in treating patients who are at high risk for breast cancer recurrence.

Timeline

Start
2001-03
Primary completion
2009-02
Completion
2009-02

Publications

  • Results Armstrong JL, Ragupathi G, Powell S, et al.: Preliminary data of vaccination of high risk breast cancer (BC) patients (pts) with a heptavalent antigen: keyhole limpet hemocyanin (KLH) conjugate plus the immunologic adjuvant QS-21. [Abstract] Proceedings of the American Society of Clinical Oncology 22: A-675, 2003.

Drugs

EvaluationDrugModalityDoseRoute
Subject Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccine Vaccine Subcutaneous
Background QS-21 Other / unclassified Subcutaneous

Indications