drugset / Trial / NCT00031187

Study of SGN-15, Antibody-Drug Conjugate, to Treat Hormone Refractory Prostate Cancer

NCT00031187 ↗

Phase 2 Completed 160 enrolled Seagen Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

SGN-15 is being investigated for therapy of patients with prostate cancer in combination with the cytotoxic agent, Taxotere. The study is an open label, randomized phase II study for patients with documented hormone refractory prostate cancer who have not had any prior therapy with Taxotere or Novantrone. Both SGN-15 and Taxotere will be administered weekly over two 6 week courses separated by a 2 week rest period.

Timeline

Start
2000-10
Primary completion
—
Completion
2003-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 35 mg/m2 —
Subject SGN-15 Monoclonal antibody 200 mg/m2 —

Indications