drugset / Trial / NCT00033254

Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases

NCT00033254

RandomizedParallel-groupOpen-labelTreatment

Summary

Randomized phase III trial to compare the effectiveness of radiation therapy with or without thalidomide in treating patients who have brain metastases. Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as thalidomide may stop the growth of brain metastases by stopping blood flow to the tumor. It is not yet known whether radiation therapy is more effective with or without thalidomide in treating brain metastases.

Timeline

Start
2002-03
Primary completion
2006-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Thalidomide Other / unclassified Oral