drugset / Trial / NCT00038883
Campath-1H and Allogeneic Blood Stem Cell Transplantation for Lymphoid Malignancies
Non-randomizedSingle-groupOpen-labelTreatment
Summary
High dose chemotherapy followed by transplantation of allogeneic hematopoietic stem cell with the use of Campath-1h, a monoclonal antibody that have a synergistic effect to chemotherapy with minimal toxicity. In addition Campath-1H can improve engraftment of donor cells through its immunosuppressive properties.
Timeline
- Start
- 2001-04-09
- Primary completion
- 2006-05
- Completion
- 2006-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alemtuzumab | Monoclonal antibody | 10 mg | Intravenous |