drugset / Trial / NCT00039052

Intravenous Interleukin-4 PE38KDEL Cytotoxin in Treating Patients With Recurrent or Metastatic Kidney Cancer, Non-Small Cell Lung Cancer, or Breast Cancer

NCT00039052 ↗

Phase 1 Completed Neurocrine Biosciences
Treatment

Summary

RATIONALE: Interleukin-4 PE38KDEL cytotoxin may be able to deliver cancer-killing substances directly to solid tumor cells. PURPOSE: Phase I trial to study the effectiveness of intravenous interleukin-4 PE38KDEL cytotoxin in treating patients who have recurrent or metastatic kidney cancer, non-small cell lung cancer, or breast cancer that has not responded to previous treatment.

Timeline

Start
2002-01
Primary completion
2003-05
Completion
2008-07

Drugs

EvaluationDrugModalityDoseRoute
Subject IL-4(38-37)-PE38KDEL Protein / enzyme biologic — Intravenous