drugset / Trial / NCT00042016

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

NCT00042016 ↗

Phase 2 Completed 40 enrolled Astex Pharmaceuticals, Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

To determine the safety and efficacy of decitabine in patients with Philadelphia chromosome-positive chronic myelogenous leukemia chronic phase that were previously treated with imatinib mesylate (STI 571) and became resistant/refractory or were found to be intolerant to the drug.

Timeline

Start
2002-07
Primary completion
—
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule — —