drugset / Trial / NCT00044564

Evaluation of Bay 59-8862 in Patients With Advanced Renal Cell Carcinoma

NCT00044564 ↗

Phase 2 Completed 54 enrolled Bayer
Non-randomizedSingle-groupOpen-labelTreatment

Summary

In patients with renal cell cancer, most frequent methods of treatment include surgery, chemotherapy, hormonal therapy, and immunotherapy. Renal cell carcinoma is usually considered to be radioresistant and chemoresistant. In patients with metastatic disease, the options are limited. The taxanes are among the most commonly used class of chemotherapy agents in clinical oncology today but they are not effective in renal cancers; the development of Bay 59-8862 targets taxane-resistant tumors and the current protocol is designed to test the safety and efficacy of Bay 59-8862 in patients with advanced renal cell carcinoma.

Timeline

Start
2001-12
Primary completion
—
Completion
2003-01

Drugs

EvaluationDrugModalityDoseRoute
Subject ortataxel Small molecule 75 mg/m2 Intravenous

Indications