drugset / Trial / NCT00045396

A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS)

NCT00045396

Phase 2 Completed 44 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Tipifarnib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. Phase II trial to study the effectiveness of tipifarnib in treating patients who have acute myeloid leukemia or myelodysplastic syndrome in first complete remission

Timeline

Start
2002-06
Primary completion
2007-10
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject tipifarnib Small molecule Oral