drugset / Trial / NCT00045500

UCN-01 and Prednisone in Treating Patients With Solid Tumors or Lymphoma

NCT00045500

Treatment

Summary

RATIONALE: UCN-01 may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining UCN-01 with prednisone may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of combining UCN-01 with prednisone in treating patients who have refractory solid tumors or lymphoma.

Timeline

Start
2002-06
Primary completion
2010-01
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject UCN-01 Small molecule Intravenous
Background Prednisone Other / unclassified Oral