A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis

Summary

Sepsis is a serious condition where there is inflammation and damage to body tissue, usually caused by an infection. This infection can lead to decreased function of vital body organs and in some cases may lead to permanent health problems or death. Much of the injury is due to endotoxin, a harmful substance produced by certain types of bacteria. An endotoxin antagonist is designed to block the effects of endotoxin. This study is designed to study the safety and efficacy when treating patients with severe sepsis.

Timeline

Start

2001-10

Primary completion

—

Completion

2005-04

Drugs

Indications