Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1

Phase 4 Terminated 100 enrolled National Institute on Drug Abuse (NIDA)

Double-blindTreatment

Summary

The purpose of this study is to test the use of High-Dose versus Regular-Dose Nicotine Patch for Nicotine Dependence in Individuals with Schizophrenia or Schizoaffective Disorder

Timeline

Start: 2001-08
Primary completion: 2005-04
Completion: 2005-04

Outcome

Outcome not reported

Stopped: “Interim data analysis showed no effect between treatment groups”

Publications

Theodoulou A, Chepkin SC, Ye W, Fanshawe TR, Bullen C, Hartmann-Boyce J, Livingstone-Banks J, Hajizadeh A, Lindson N. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2023 Jun 19;6(6):CD013308. doi: 10.1002/14651858.CD013308.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nicotine	Unknown	21 mg	Other
Subject	Nicotine	Unknown	42 mg	Other