drugset / Trial / NCT00050596

Comparison Study of MDX-010 (CTLA-4) Alone and Combined With Docetaxel in the Treatment of Patients With Hormone Refractory Prostate Cancer

NCT00050596 ↗

Phase 2 Completed Bristol-Myers Squibb
RandomizedCrossoverOpen-labelTreatment

Summary

The primary objectives of the study are to determine the safety and activity of multiple doses of MDX-010 in patients with hormone-refractory prostate cancer (HRPC), and to determine the safety and activity profile of a single dose of cytotoxic chemotherapy (docetaxel) in combination with MDX-010

Timeline

Start
2002-11
Primary completion
2004-11
Completion
2004-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule — —
Subject Ipilimumab Monoclonal antibody — —

Indications