drugset / Trial / NCT00052208

Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

NCT00052208

Phase 1/2 Completed 158 enrolled National Cancer Institute (NCI) NRG Oncology · collab
NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the side effects and best dose of gefitinib when given together with radiation therapy and to see how well it works in treating patients with glioblastoma multiforme. Gefitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x rays to kill tumor cells. Giving gefitinib together with radiation therapy may be an effective treatment for glioblastoma multiforme.

Timeline

Start
2002-03
Primary completion
2005-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Gefitinib Small molecule Oral