drugset / Trial / NCT00054483
Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction
NaSingle-groupOpen-labelBasic science
Summary
Phase I trial to study the effectiveness of bortezomib in treating patients who have advanced cancer and kidney dysfunction. Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.
Timeline
- Start
- 2003-01
- Primary completion
- 2009-09
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bortezomib | Small molecule | — | Intravenous |
Indications
Burkitt lymphoma
MALT lymphoma
Waldenstrom macroglobulinemia
cancer of unknown primary site
chronic lymphocytic leukemia/small lymphocytic lymphoma
extranodal nasal NK/T cell lymphoma
grade III lymphomatoid granulomatosis
large-cell immunoblastic lymphoma
mantle cell lymphoma
nodal marginal zone B-cell lymphoma
plasma cell myeloma
splenic marginal zone lymphoma