drugset / Trial / NCT00054639
Oblimersen Sodium and Rituximab in Treating Patients With Recurrent B-cell Non-Hodgkin Lymphoma
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to learn if the combination of oblimersen sodium and rituximab can help to shrink or slow the growth of the tumor in patients with B-cell non-Hodgkin's lymphoma who have not responded to earlier treatment. Oblimersen Sodium is an investigational drug. The safety of this combination treatment will also be studied
Timeline
- Start
- 2003-01
- Primary completion
- 2010-01
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rituximab | Monoclonal antibody | — | Intravenous |
| Subject | oblimersen sodium | Antisense oligonucleotide | — | Intravenous |
Indications
Burkitt lymphoma
MALT lymphoma
Waldenstrom macroglobulinemia
chronic lymphocytic leukemia/small lymphocytic lymphoma
grade III lymphomatoid granulomatosis
intraocular lymphoma
large-cell immunoblastic lymphoma
mantle cell lymphoma
nodal marginal zone B-cell lymphoma
primary cutaneous B-cell lymphoma
small intestine lymphoma
splenic marginal zone lymphoma
testicular lymphoma