Safety, Tolerability and Effectiveness of Natalizumab in Adolescents With Active Crohn's Disease

Summary

The purpose of this study is to determine the safety and tolerability of natalizumab in adolescents (ages 12-17) diagnosed with moderately to severely active Crohn's disease (CD). It is thought that natalizumab may stop the movement of certain cells, known as white blood cells, into bowel tissue. These cells are thought to cause damage in the bowel leading to the symptoms of Crohn's disease. Patients who complete this study may be eligible for long-term natalizumab therapy via extension protocol ELN100226-352.

Timeline

Start

2002-04

Primary completion

2004-05

Completion

2004-05

Drugs

Indications