Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine

Phase 4 Completed 65 enrolled University of Maryland, Baltimore National Institute of Mental Health (NIMH) · collab Ortho-McNeil Janssen Scientific Affairs, LLC · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will determine whether adding the drug risperidone (Risperdal®) is more effective than placebo in treating schizophrenic patients who are taking the drug clozapine.

Timeline

Start: 2001-12
Primary completion: 2007-12
Completion: 2007-12

Publications

Weiner E, Conley RR, Ball MP, Feldman S, Gold JM, Kelly DL, Wonodi I, McMahon RP, Buchanan RW. Adjunctive risperidone for partially responsive people with schizophrenia treated with clozapine. Neuropsychopharmacology. 2010 Oct;35(11):2274-83. doi: 10.1038/npp.2010.101. Epub 2010 Jul 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Risperidone	Other / unclassified	4 mg	—

Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine

Summary

Timeline

Publications

Drugs

Indications